2022-RA-1682-ESGO Diagnostic accuracy of three-dimensional transvaginal ultrasound for detecting congenital uterine anomalies: systematic review and meta-analysis

Introduction/Background The aim of this study is to evaluate the accuracy three-dimensional transvaginal ultrasound (3D-TVS) for diagnosis uterine mullerian anomalies (UMA), using surgery as reference standard. Methodology A search was performed in PubMed/MEDLINE, CINAHL, Scopus, Cochrane and Web Science databases (January 1990 December 2021) studies evaluating diagnostic performance 3D-TVS detecting UMA, endoscopic findings test. Quality Assessment Diagnostic Accuracy Studies-2 (QUADAS-2) tool used quality studies. Pooled sensitivity, specificity, positive negative likelihood ratio were calculated all types separately septate bicornuate uterus, specifically. Arcuate uterus considered normal. Post-test probability UMA following a or test determined. Results identified 297 citations after excluding duplicates. After further exclusions, fourteen ultimately included qualitative quantitative syntheses, comprising 1776 women. Fourteen analyzed presence any type seven by subgroups (septate and/orbicornuate uterus). mean prevalence 47% (range: 1%-97%). Overall, pooled ratios are shown table 1. Heterogeneity high. According QUADAS-2 tool, most high risk bias patient selection, low index standard unclear flow/timing. Conclusion Our results confirm diagnosing anomalies. These data support role technique gold these